The physiological function of Hydroxycinnamic Acid

Detoxification: combined with poisons or Pueraria Mirifica Extract to eliminate their toxic effects;

Participate in redox reaction: as an important reducing agent, participate in various redox reactions in vivo;

To protect the activity of Tribulus Terrestris Extract: to keep sh, the active group of thiolase, in a reduced state [5];

Maintain the stability of erythrocyte membrane structure: Rosemary Leaf Extract the damaging effect of oxidant on erythrocyte membrane structure.

Mechanism of action

GSH, as an important metabolic regulation substance in cells, is not only the cofactor of glyoxalase and malonaldehyde, but also the cofactor of glyceraldehyde phosphate dehydrogenase. GSH participates in the tricarboxylic acid cycle and sugar metabolism in vivo, and can activate many enzymes, such as mercapto (SH) enzyme coenzyme, so as to promote the metabolism of sugar, fat and protein. GSH is characterized by active sulfhydryl (- SH), which is the most important functional group. It can participate in various important biochemical reactions of the body, protect the sulfhydryl group of important enzyme protein from oxidation and inactivation, and ensure energy metabolism and cell utilization. At the same time, it can directly reduce the free radicals to acidic substances by the combination of sulfhydryl and free radicals in the body, so as to accelerate the excretion of free radicals and fight against the damage of free radicals to important organs. Haddad et al. Found that GSH is involved in the regulation of lipopolysaccharide induced cytokine transcription and i-kb / NF-kB signaling pathway. Armstrong et al. Found that the decrease of GSH content is a potential early activation signal of apoptosis, followed by the production of oxygen free radicals to promote apoptosis.